Some medications can affect sexual desire and function. For example, PDE5 inhibitors like sildenafil and tadalafil, primarily used to treat erectile dysfunction, can also increase libido. Flibanserin, a drug that treats hypoactive sexual desire disorder (HSDD) in premenopausal women, works by affecting serotonin and dopamine levels, which can increase sex drive. Additionally, gonadotropin-releasing hormone agonists and steroidal anti-androgens are used to manage overwhelming sexual desire. Synthetic aphrodisiacs like MDMA and methamphetamine can also increase sexual desire